It is widely recognized that aging is the leading risk factor for dementias such as Alzheimers disease. But exactly why does cognitive function decline with age in many people, but not in others?
JAXs Kaczorowski lab revealed a gene associated with cognition and aging, from studies in the Diversity Outbred DO mouse panel, now in Cell Reports
JAX.ORG
Genetically diverse mice reveal a mechanism of cognitive decline
Cross-species analyses identify Dlgap2 as a regulator of age-related cognitive decline and Alzheimers dementia.
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